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      Bismuth & Lithium
 
Although not related on the Periodic Table of Elements, Bismuth (Bi) and Lithium (Li) share left / right-sided
cell receptors and may be considered essential to human health, although neither one has been officially des-
ignated to be essential at this time.  Bismuth and lithium are biologically associated on a gastrointestinal and
mental health level.  While lithium is better known for its therapeutic properties with manic-depressive / bipolar
disorder, both elements exert a similar effect on their respective chemical environment:  Lithium in regard to
potassium / sodium balance (all right-sided cell receptors), and bismuth in regard to phosphorus / zinc
balance (all left-sided cell receptors).

Shared toxicity or overdose symptoms of bismuth and lithium include possible kidney or liver damage, hypo-
adrenalism (bismuth), hypothyroidism (lithium), mental confusion, staggering gait, tremor, among others.
Magnesium can be used to treat lithium overdose, while calcium can be used to treat bismuth overdose.  In
addition to treating patients with Manic-Depressive Illness, lithium has also been used with some success
for Ménière's disease, Huntington's Chorea, and alcoholism.

Raising below-normal levels of lithium or bismuth can, but does not have to produce any positive effects in
regard to mental health, since few lithium or bismuth-deficient individuals present with actual mental illness,
although some researchers claim that areas with the highest lithium levels in drinking water have the lowest
rates of homicides, and the lowest mental hospital admissions (those findings have not been officially
accepted).

When indeed indicated for bipolar disorder, patients typically present with low lithium levels and very high
high sodium levels, whereby lithium provides a balancing effect, otherwise the intake of higher amounts of
lithium has a tendency to raise sodium, and frequently also potassium through its effect on kidney functions,
as well as manganese (through its effect on liver functions), so there is a distinct biochemical conflict that has
a genetic basis, otherwise everyone with low lithium levels - which are actually quite common - would be
suffering from manic-depressive episodes.

Both, bismuth & lithium, frequently test low in patients who suffer from low stomach acid levels corresponding
to upper (bismuth) and lower (lithium) parts of the stomach, and they are invariably always low in those with an
active infection of the Helicobacter Pylori bacterium, which is responsible for some gastric ulcers and a
number of other medical conditions (see Acu-Cell "H. Pylori" for details).
Bismuth, through its antimicrobial action, is more appropriate for peptic involvement to inhibit H.Pylori activity,
where it supports an increase in upper stomach acid levels, while lithium is more indicated for lower gastric /
duodenal involvement, where it supports an increase in lower stomach acid levels.  ¤
===================================================================================
Dietary Reference Intake (DRI) is the latest term replacing daily dietary reference values such as
Adequate Intake (AI), Tolerable Upper Intake Level (UL), Estimated Average Requirements (EAR),
Nutrient Reference Value (NRV),  and Recommended Dietary Allowance / Intake (RDA / RDI).

Bismuth:Lithium:

DRI (RDA):NoneDRI (RDA):None

Estimated daily intake of bismuth: 2mcg - 30mcg,Estimated daily intake of lithium: 30 - 100mcg+

Therapeutic Range:50mcg - 525mg+Therapeutic Range:50mcg - 1500mg+
___________________________________________________________________________________

Cellular / Intracellular Attributes and Interactions:

Bismuth Synergists:Lithium Synergists:
Germanium, iron, nickel, phosphorus, Silicon, manganese, cobalt, sodium, Vitamin D,
Vitamin D,*[Vitamin C],

Bismuth Antagonists / Inhibitors:Lithium Antagonists / Inhibitors:
Calcium, copper,Magnesium, chromium,
 *[inositol, caffeine, sodium, vanadium],

 * with chemical imbalances (bipolar disorder),

Low Levels (Deficiency - Symptoms and/or Risk Factors) Therapeutic Indications:

Bismuth:Lithium:
Gastrointestinal disorders, low stomach acid,Gastrointestinal disorders, low stomach acid
(upper part of stomach), heartburn, bloating,(lower part of stomach), heartburn, bloating,
calcification, warts, diarrhea, gastric ulcers,Bipolar / manic-depressive disorder,

High levels / Overdose / Toxicity / Negative Side Effects - Symptoms and/or Risk Factors:

Bismuth:Lithium:
Mental confusion, memory problems, tremors,Nausea, vomiting, weight gain, staggering gait,
staggering gait, muscle twitching, slurring speech,hypothyroidism / goiter, tremors, liver disease,
joint problems, hypoadrenalism, hearing and visualkidney disease, frequent urination, lethargy,
disturbances, hallucinations, coma,diarrhea, slurring speech, edema, death,
___________________________________________________________________________________

Bismuth Sources:Lithium Sources:
Water, foods, cosmetics, stomach remedies,Some mineral waters, seaweed, sugarcane. ¤

===================================================================================
===================================================================================

General recommendations for nutritional supplementation:  To avoid stomach problems and promote better
tolerance, supplements should always be taken earlier, or in the middle of a larger meal.  When taken on an
empty stomach or after a meal, there is a greater risk of some tablets causing irritation, or eventually erosion
of the esophageal sphincter, resulting in Gastroesophageal Reflux Disease (GERD).  It is also advisable not
to lie down immediately after taking any pills.  When taking a very large daily amount of a single nutrient, it is
better to split it up into smaller doses to not interfere with the absorption of other nutrients in food, or nutrients
supplemented at lower amounts.

___________________________________________________________________________________
Copyright © 2000-2010  Ronald RothAcu-Cell Nutrition: Lithium & Bismuth
  
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