=================================================================================== << Page 1 Page 2 DRI / RDA for Nickel & Cobalt + Vit C, E, B12, B15: =================================================================================== Dietary Reference Intake (DRI) is the latest term replacing daily dietary reference values such as: Adequate Intake (AI *), Nutrient Reference Value (NRV), Tolerable Upper Intake Level (UL), Estimated Average Requirements (EAR), and Recommended Dietary Allowance / Intake (RDA / RDI). Nickel: Cobalt: DRI (RDA) : 300mcg - 700mcg DRI (RDA) : 10mcg - 20mcg Therapeutic Range : 500mcg - 50mg+ Therapeutic Range : 50mcg - 1mg ___________________________________________________________________________________ Cellular / Intracellular Attributes and Interactions: Nickel Synergists: Cobalt Synergists: Iron, tin, phosphorus, Vitamin C, bismuth, [cobalt], Manganese, sodium, Vitamin B12, iodine, [nickel], germanium, Nickel Antagonists: Cobalt Antagonists: Manganese, zinc, calcium, copper, [cobalt], Potassium, iron, magnesium, chromium, [nickel], sodium, Vitamin E, phytic acid, phosphorus, Vitamin C, protein, Low Levels / Deficiency - Symptoms and/or Risk Factors: Nickel: Cobalt: Hyperglycemia (high blood sugar), low blood May lead to pernicious anemia, severe fatigue, pressure, depression, liver disease, anemia, shortness of breath, low thyroid, low stomach acid, sinus congestion, fatigue, low adrenals, High levels / Overdose / Toxicity / Negative Side Effects - Symptoms and/or Risk Factors: Nickel: Cobalt: Angina, skin rash, hypoglycemia (low blood sugar), Angina, panic-anxiety attacks, shortness of breath, decreased estrogen, shortness of breath, asthma, asthma, cardiomyopathy, congestive heart failure, nausea, vomiting, diarrhea, headache, lowered pulse, polycythemia, thyroid problems, overproduction of increased protein in urine, increased red blood cells, red blood cells,neurological problems, skin rash, heart failure (from 50,000 - 100,000 x the daily intake), red blood cells, dermatitis, ___________________________________________________________________________________ Nickel Sources: Cobalt Sources: Unrefined whole grains, nuts, oysters, tea, herring, Buckwheat, dairy, figs, green leafy vegetables, buckwheat seed, peas, beans, soybeans, lentils, cabbage, meats, shellfish, sea vegetables, ___________________________________________________________________________________
___________________________________________________________________________________ Vitamin C / Ascorbic Acid: Vitamin E / (Alpha) Tocopherol: DRI (RDA): DRI (RDA): 1mg = 1IU for details see Vitamin C Supplementation 0-12 months 40-50mg 0-12 months 4-5mg 1-10 years 20-25mg 1-10 years 6-10mg 11-18 years 45-75mg 11-18 years 11-15mg 18 years + 75-90mg+ 18 years + 15mg+ pregnant / lactating + 45mg pregnant / lactating + 4mg Therapeutic Range: 250mg - 25,000mg+Therapeutic Range: 100mg - 2000mg+ Low Levels / Deficiency - Symptoms and/or Risk Factors: Vitamin C: Vitamin E: Scurvy, slow wound healing, anemia, easy bruising, Increased oxidation of free radicals, increased shortness of breath, fatigue, nosebleeds, frequent ridk for various cancers, cardiovascular disease, infections, gastrointestinal problems, depression, hemolytic anemia, angina (left-sided), leg cramps, chronic gingivitis, increased risk for various cancers, increased lipid peroxidation, dry skin, irritability, impaired formation and maintenance of collagen, reproductive abnormalities, miscarriage, PMS, impaired multiple hormonal functions, dermatitis, fibrocystic (breast) disease, gallstones, cataracts, arthritis, reduced insulin production, some types of bruising, dermatitis, male infertility, vascular degeneration, gallstones, High levels / Overdose / Toxicity / Negative Side Effects - Symptoms and/or Risk Factors: Vitamin C: Vitamin E: Diarrhea, abdominal cramps, high stomach acid, Altered immunity, altered blood clotting, fatigue, increased urination, insomnia, irritability, joint reduced thyroid functions, increased Vitamin C, pains, osteoporosis, headaches, hypoglycemia, Vitamin A, or calcium requirements, cardiovascular weakness, reduced estrogen, PMS, may increase cardiovascular disease / stroke, muscle weakness, infections by causing copper deficiency, reduced headaches, raised or lowered blood pressure, estrogen, reduced progesterone, reduced prolactin. nausea, ___________________________________________________________________________________ Vitamin C Sources: Vitamin E Sources: Citrus fruit, green peppers, sweet and hot peppers, Wheat germ, seeds, nuts, sweet potato, whole potatoes, rose hips, currants and other berries, kale, unrefined grains, vegetable oils, olives, corn, tomatoes, broccoli, cabbage, spinach, watercress, apricot oil, margarine, green leafy vegetables. ___________________________________________________________________________________
Vitamin B12 - Hydroxy or Cyanocobalamin: Vitamin B15 - Pangamic Acid: * (also available as adenosyl or methylcobalamin) (also called calcium pangamate) DRI (RDA): DRI (RDA):* 0-6 months 0.5mcg 6-12 months 1.5mcg * no USRDA [may be substituted with DMG ]. 1-18 years 2-3mcg 18 years + 3-4mcg 18 years + 25mg pregnant / lactating + 1mcg Therapeutic Range: 50mcg - 10mgTherapeutic Range: 50mg - 500mg+ Low Levels / Deficiency - Symptoms and/or Risk Factors: Vitamin B12: Vitamin B15: Pernicious anemia (numbness and tingling in Angina (right-sided), coronary artery spasms hands and feet / nerve damage), shortness of (right-sided), some types of panic-anxiety disorder, breath, severe fatigue, birth defects, dementia, headaches, Vitamin B12 overdose (from Vit B12 confusion, poor memory, depression, reduced injection), some types of high blood pressure, WBCs and platelet formation, loss of appetite, shortness of breath, asthma, increased lactic acid, weight loss, sore tongue, headaches, nausea, learning difficulties, High levels / Overdose / Toxicity / Negative Side Effects - Symptoms and/or Risk Factors: Vitamin B12: Vitamin B15: Can cause low folate-related anemia, hyperthyroid, Severe fatigue, pernicious anemia (long-term very numbness / tingling in right arm or face, hypokalemia, high intake), depression, headaches, skin rash, anxieties, panic-anxiety attacks, heart palpitations, shortness of breath, nausea, increased Vitamin B12 insomnia, increased Vit B15 requirements, skin rash, requirements, optic nerve atrophy (in someone with Leber's disease), some types of leukemia, liver and kidney diseases, may worsen symptoms of mitral valve prolapse, may increase / stimulate tumor / cancer cell division. Methylcobalamin is the preferred form of Vit B12 if cyanocobalamin is not tolerated, however side effects (although rare) are possible with all forms. ___________________________________________________________________________________ Vitamin B12 Sources: Vitamin B15 Sources: Meat, dairy, eggs, seafood. [Vit B12 is only found in Brewer's yeast, whole grains, organ meats, seeds, animal products, but has been obtained through insect brown rice, or feces-contaminated grains, fruits, or vegetables]. ¤ ___________________________________________________________________________________ << Page 1 Acu-Cell - Nickel & Cobalt Page 2 ___________________________________________________________________________________
=================================================================================== General recommendations for nutritional supplementation : To avoid stomach problems and promote better tolerance, supplements should always be taken earlier, or in the middle of a larger meal. When taken on an empty stomach or after a meal, there is a greater risk of some tablets causing irritation, or eventually erosion of the esophageal sphincter, resulting in Gastroesophageal Reflux Disease (GERD). It is also advisable not to lie down immediately after taking any pills. When taking a very large daily amount of a single nutrient, it is better to split it up into smaller doses to not interfere with the absorption of other nutrients in food, or nutrients supplemented at lower amounts. ___________________________________________________________________________________ Copyright © 2000-2010 Ronald Roth DRI / RDA of Cobalt & Nickel + Vitamin C / E / B12 / B15
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