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Intracellular Calcium Measurement with microelectrodes
Intracellular Calcium Measurement with microfluorometry
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Cellular Nutrition

                  

What is Cellular Nutrition, and why use a Cellular Analysis

         

to determine Trace Mineral Status, rather than Serum Measurements?


Dietary requirements of minerals and their levels are nearly impossible to establish using routine blood tests.
Most electrolytes (calcium, magnesium, potassium...) [1] are subject to close homeostatic regulation regardless
of dietary intake, while the accuracy of their measurements is compromised by collection, transport, hemolysis,
storage, mineral ratios, or processing used.
Similar errors are encountered when trying to establish
nutritional requirements through serum or plasma panels
for zinc, manganese, phosphorus, chromium, selenium,
copper, and most other trace elements.

While an antioxidant-rich diet may provide adequate
cellular nutrition for the average, healthy individual,
it would be inadequate for those suffering from nutrition-
related chronic diseases, which require the use of more
sophisticated resources that are capable of measuring
and optimizing an individual's cellular nutrition status.
Acu-Cell Technology - presents 38 years of non-sponsored, independent research and patient studies on
Cellular Nutrition as measured with Acu-Cell Analysis.™
Acu-Cell Analysis - compares conventional lab tests with intracellular measurements in the assessment of
essential trace minerals, flavonoids, Vitamin B12, stomach acid, thyroid, adrenals, lipid status, and others.
Acu-Cell Nutrition - covers the synergism, antagonism, toxicity, deficiency signs & symptoms, and DRI/RDA
of vitamins, minerals, bioflavonoids, and associated nutrients, as applicable to cellular nutrition.
Acu-Cell Disorders - profiles an A - Z list of common medical conditions and their relationship to nutritional
excesses and deficiencies.
Diets & MLM - looks at various diets, multi-level-marketing products, coral calcium, the blood type diet, plant
sterols, vegetarianism, chocolate products, Vitamin C supplementation, sugar / glycemic index & satiety index.
Mineral Ratios - offers a clinical perspective on the importance of maintaining a proper mineral ratio between
calcium, magnesium and other elements, and it looks at the relationship of mineral ratios to spinal alignment.
Tin - Health Effects - presents research results on the effects of the element tin on adrenal functions,
depression, fatigue, and a number of other health concerns.
Antiviral Remedies - lists natural remedies for the Common Cold & Flu for a normal, weak, and overactive
Immune System.  Also applicable for a Pandemic Flu such as H1N1 (Swine Flu), or H5N1 (Avian / Bird Flu).
Spiritual Health - offers a Biblical view on Spiritual Health, Suicide, Physician-assisted Suicide, & Euthanasia.
Myth:  If one has a healthy diet, one does not need any supplementation.
Fact:  If a large group of people were to follow the exact same dietary lifestyle & exercise program, a certain
number would still suffer from high or low blood pressure, high or low blood sugar, or high or low stomach acid,
while the rest may develop arthritis, cardiovascular disease, cancer, mental illness, or other medical conditions.
Most nutrition-related conditions in the Western world are not caused by nutritional deficiencies such as
scurvy, pellagra, beriberi, or rickets, but nutritional imbalances, which negatively impact cellular nutrition
and are responsible for many common medical problems, while metabolic disorders can cause nutritional
deficiencies following the malabsorption of certain nutrients.

Age-related hormonal imbalances, and diminishing renal capacity also affect nutritional requirements.
Without adequate androgenic (DHEA) support, minerals such as zinc or potassium will frequently become
depleted even when maintaining the same - and previously adequate dietary intake.
Failure to compensate for these deficiencies contributes to the risk of developing blood sugar, blood pressure,
weight, and/or a variety of hormone imbalance-related organic problems, including cancer.  Neither a "healthy"
diet, nor standard multi-vitamin / mineral formulations will be helpful in these cases since the nutrients from
these sources are not customized to match specific cellular nutrition requirements of a patient, so abnormal
mineral levels or ratios remain unchanged.

One's genetic background has an even greater impact to promote, or help resist the development of a wide
range of medical conditions.  As a result, only individualized supplementation, based on someone's cellular
chemistry and genetic background has the best potential to resolve these medical disorders nutritionally,
while specific dietary changes or nutritional programs alone may be helpful in less serious medical conditions.

Myth:  After menopause, every female needs to supplement extra calcium.
Fact:  There is no magic age when either females or males suddenly need to adjust their calcium intake.  In
contrast to a number of other nutrients whose requirements tend to change with advancing age, requirements
for calcium are dependent on multiple genetic, metabolic, and lifestyle factors, none of which are gender or
age-related.  Only with pregnant or lactating females it may be justified to increase their calcium intake by
about 200 - 300 mg per day to cover additional needs for the baby.

However, even then it is far better to assess individual requirements, since officially recommended amounts
would be totally inadequate when there is a history of the mother being chronically calcium deficient, which
increases the risk of birth defects in the baby, while at the same time there are plenty of pregnant women
whose calcium levels are perfectly adequate, or even on the high side, without extra supplementation.

This is no different than what applies to the general population, where some patients (regardless of age
or gender) suffer from chronic calcium deficiency and require rather large amounts of extra calcium to meet
requirements, while the opposite applies to many other patients who suffer from chronic calcium overload.
While an individual assessment would be the logical solution in both instances, there are no routine lab tests
at this time that accurately assess a patient's calcium requirements.
Without utilizing cellular nutrition technology, the "one-size-fits-all" recommendations used by most doctors
for postmenopausal women (and all other patients) not only perpetuate the dilemma for those with calcium
assimilation problems, but they also add to the woes of those who retain too much calcium.

A younger body is generally much more forgiving when dealing with high calcium levels, however with every
decade, excessive calcium intake, or excessive storage due to a lack of calcium co-factors, will take an
increasingly irreversible toll by calcifying an individual's organs, joints, and/or cardiovascular system, in
addition to causing a negative impact on stomach acid levels, mood, energy, and general mineral balance.

2013 Calcium Update:  Following the conclusion of two 2012 studies by New Zealand researchers, which
claimed that calcium supplements might increase the risk of heart disease, proposals were made to update
physician guidelines to discourage patients from supplementing extra calcium.  A subsequent study published
in the American Journal of Clinical Nutrition found no link between supplemental or dietary calcium intake and
coronary artery calcification, however in the latest (2013) turn of events, a Swedish study again linked a
higher dietary and supplemental intake of calcium to a greater risk of dying from heart disease!

For the time being, until guidelines are officially revised, patients are advised to continue with present rec-
ommendations on their calcium intake, which will continue to benefit individuals who are chronically calcium
deficient, but it will unfortunately also continue to worsen those who suffer from calcium overload.[84]

Myth:  One may liberally supplement mega-doses of water-soluble vitamins since they -
unlike fat-soluble vitamins - are not stored in the body, so they cannot cause any harm.
Fact:  Despite being water-soluble, Vitamin B6 can cause permanent, irreversible nerve damage when used
improperly, while an excessive intake or overdose of Vitamin C has the potential of eventually causing zinc,
copper, or calcium deficiencies in prone individuals.
Many nutrients do not have to be stored in the body in high amounts to be able to cause, or contribute to
disease.  While being metabolized, even water-soluble nutrients interact with other nutritional elements either
as synergists or antagonists, and as such are capable of worsening mineral ratios and overall cellular nutrition
balance when overdosed on, which over time establishes a favorable environment to develop medical problems.

Claim:  Following the official Food Pyramid or Food Guide is key to a healthy, long life.
Fact:  While this 'Eat your Fruits and Vegetables' cliché has been made out to be the panacea to good health,
that advice benefits those most who inherited superior genes, but has only a moderate impact, or can even be
detrimental to many patients who have inherited, acquired, or are nursing specific health problems involving
the digestive tract or immune system.
Even if they wanted to, those with a less favorable genetic make-up, or different cellular nutrition requirements
as a result of it, cannot follow many of these "get healthy" recommendations because they are allergic to, don't
tolerate, or have other problems with the very foods that are supposed to make, and/or keep them healthy!

Claim:  Some researchers suggest that nutritional supplements either do not help,
or worsen certain conditions.
Fact:  This is no less surprising than randomly choosing a drug, randomly treating a medical disorder, and then
arriving at the same conclusions.  One obviously needs to match the right nutrients and the right amounts
to a patient's specific medical situation if one intends to go beyond deficiency-preventive measures in an
attempt to rectify more difficult-to-treat medical disorders nutritionally!

In contrast to Drug Research, which tends to focus on single, concentrated ingredients, Nutritional Research
- and especially Cellular Nutrition Research - yield much better results when using complexed nutrients.  So
instead of taking plain ascorbic acid, Vitamin C needs to be complexed with adequate amounts of bioflavonoids
such as rutin and hesperidin, to duplicate more food-like benefits.
The same applies to supplementing Mixed Carotenoids, which include alpha-carotene, lycopene, zeaxanthin,
cryptoxanthin, and lutein - instead of taking (synthetic) beta-carotene alone.  Equally superior is taking a
Vitamin E Complex in the form of alpha, beta, gamma, delta tocopherols, and alpha, beta, gamma, delta
tocotrienols, rather than taking large, single amounts of dl-alpha tocopheryl alone.

Instead of developing or presenting new concepts in Clinical Nutrition or Cellular Nutrition, some "researchers"
are wasting everyone's time with negative, or misleading headlines, trying to impress the public with what is
frequently rehashed old news.  Real experts on nutrition are well aware that common vitamin pills, particularly
the non-complexed or synthetic variety are no panacea for everything that ails society, and they would not
make any claims to that effect.  Resolving more complex medical conditions nutritionally requires an equally
more advanced cellular technology, that analyses a patient's intracellular chemistry to establish precise,
person-specific requirements - not population averages.
healthy Fruit
Intracellular Calcium Measurement in neurons with
calcium-selective microelectrodes, and microfluorometry
Do all people require nutritional supplements to maintain good health?
When one analyzes people living to a ripe old age in reasonable health without the need of supplementation,
one finds that they had a lot of odds in their favor.  It usually starts with excellent genes, followed by a lack
of factors that tend to upset the biochemical balance necessary to maintain good health.  Anything upsetting
that cellular nutrition balance will either shorten someone's life, worsen its quality, or require compensation
through extra nutritional support or drug intervention.  A centenarian who never touched a supplement in his
life has likely maintained such a balance as a result of little "pro-oxidant" activity, which necessitated little
"antioxidant" activity -- just to mention one example.
On the other hand, let's assume a very healthy individual with similar longevity odds in his favor ends up with
a serious trauma early in life.  The imbalance introduced to his previously sound chemistry by drug treatments
or organ damage will have him for the rest of his life search for compensatory factors to improve the quality
of life.  Unlike before his injury, he is now in the same situation as those born less fortunate health-wise, and
may now have to become more reliant on better nutrition and/or additional supplementation.  So the reason
for supplementation, and the dosages required, can change with individual circumstances.

The difference between individuals who take nutritional supplements (that match cellular nutrition requirements),
and those who do not, can perhaps be compared to younger versus older people facing the same medical crisis.
Younger people simply tend to handle various medical situations better, or recover faster than older ones, so
the right nutritional supplementation may perhaps be compared to lowering someone's biological age. ¤
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Updated:  6. Aug. 2014
by Dr. Ronald Roth
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